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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5897e269f346fa8602f5ba7cdd67de76a0090dc9ce7938103601d58f0418f8c' 
  AND token = '1EiWDUhJfSvnOwJZkx5Y/hTFNBTcq6fNM5pUvU8h/RI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}