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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '648a71b051f2b83595a20a9a10755d59f9bb2060c90a2d8b14e278d5826a985e' 
  AND token = 'RcBQMPL4IIQ/KoI0rLmhpRoUsb9vAMnL43jEQsI18mk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}