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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22c1f00ae8737e1c040c4a0dad40e8abce8104e9537f59f1f9cf4955df6473a4' 
  AND token = '90ILsWnB3e+xYiFPC16zuWb6pwcncpEXjdF9exXs9sA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}