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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17bebadb6c790ca01561e8f5b9c485b08ed870ece5ab0d9e846f289beed67306' 
  AND token = 'gdvNnWvYmPvEliaoQKAiD91zf96aceHN/2aBth/ejxE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}