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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b21564f1b104358bb86265a87263f81d683d3f7221fdbeeb92a36de2781c298' 
  AND token = 'cle4am4ON4d0qan0WRyZ1IHm5bqeYFziBmONdrEjFsE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}