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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3efa6a14c2d9a4f57109fcbd002146c7b3def02776de112c143f1842df47c4a5' 
  AND token = 'Zja2PEAhHJTR6Rf9lq30URPIU9ArtzEDE+u5TeK5pYI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}