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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b6c0823ea36ff3cffa310f3a4143b3828d7f0741a1cd1f5cbd8ff087e51225c' 
  AND token = 'CNov6vfSC+SVXKFiEQ5Eyzg46iYfBRi5YSkFrO45bJQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}