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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e42cb9fe7ae20a0d42130615269f0660d4a0928575596925f719676d1b95aa28' 
  AND token = 'W8ri/oSIhB7R48TpIah9QvrjBfCLodGIpWF3RsxJbvA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}