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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce12e3688da5042ba072e78e72cdf0f99da68d678479ab5dc2cbecebdb9df255' 
  AND token = '9MbMCFd6mapItvsJrxvhllH3GyTSfM18devy60ENbf4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}