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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe22ed375a1a9d44378374c349ab4d7c3c11f1f6e356a7de1cdeb188e043e6cd' 
  AND token = 'vZZJsNALDFigDmMd8XeB63qoAkup+lzIE6BjObQJ5b8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}