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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d29d87bee9007c2ba58ba9ae07698c2fead14a355e9d319b9f5f6d5e1e85898' 
  AND token = 'bwEmN+HGZ5v5M8F/vq4J/0bkSqPHknK5U5uixEExMz0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}