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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3074eeba9200d3345fc3f822799ef0fb10e6d7dafc8161e9b18b78cf6f9398c' 
  AND token = 'l9SKe6hTJOQlbtK/RkGgl9994kXP9AVfzpWHp4Yl08c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}