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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a924a9db0f57a5da82cf2ecd2ebad2837919216c9383f2d8731d20af2a81013' 
  AND token = 'wEVNie/M/VZC6f0LBrl8GylEP9lc0eEsZvoLM/oK0L0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}