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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c27b272e30c322708024548fcb03c044e309017511ee1a963dbd71aec5fb37d6' 
  AND token = '6ur7kUdm5pAT7UxNO8BGKaU184VunHy0owZiBRXCHAI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}