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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f1cb0a8030bb433bfe285c15ea831f771bf64fae83104ab0db98e4c3de50b56' 
  AND token = '42pN6Yw4SrxRmvxqHOhvFSeSJYmQhXJZrwOxZUd4hfI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}