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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '639ed3be7aa022f0724c146f7170e61a57e041b1755c92fa0e465a73d3d76f08' 
  AND token = 'VMtA7/NnFpdnI+ickKbuLDZytwaM/3Q0vj+Do3eHJVQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}