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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d63f0c263d611c7aae07612356dc32de96e5b40a97ffd858bdd6283bf480432' 
  AND token = 'XSHr/Cm+qBDcOdRD8PS+lfWnHSd3pFlMpc04En8kais=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}