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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de1f08c17af6c7ba5b146c95325d48f9fbec56c9b05f11e7765c1ac342367b3d' 
  AND token = 'lQAO+9LS0dDJqzkkjkuw3TQc5lrfovBzT8IQ37olpZs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}