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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d650fce5730035a58728f1c1a6be1e0907868e17df701500190a10f5203e090' 
  AND token = 'yYvcIRsw78aJBVz6f9ijMTCh3hi2n4IUkjaEC4IwA3s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}