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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51ede0a15e0097e600139be5a7a683d492022c1f5204ba8d56585fa66864d0c7' 
  AND token = 'NYIW8/M1FnHCr+O5vsInylKn4IlZaJ3WF6kuR0px3L0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}