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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f54fb670b6df945394399d0a42b6f164c66d7f55c026bcbd0f1ec83c9f6978ae' 
  AND token = 'dprMMiIj+3K7kL6sNZYTxRd+eJAO7uD2QMdPmU4ny8U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}