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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c499a0d63d44f4c36fb17ec47f26dfa254f4bc6c00d729b98c9dff127006780' 
  AND token = 'y5WvKLEDu9ihGi1jTFe/rqkzCW58vSZTZc9iJ6SAtv0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}