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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '145ecb084b1872228c2459a37d8e0e599e2eacf4844f2272b1c49b046f81a2cf' 
  AND token = 'ezPEVcLMw4yT+0HF3AQZswEI9wEHfna+fo8ikiywY5k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}