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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a16f7972bdf859970142fc371a10a5607fdc8a265043f2b970834f49a9e8528c' 
  AND token = 'VZLaMNFbshpnu6OtVZ+qsTOh99T66AdmQnor+D2nQTk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}