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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e018835941961362240fdcddbbdfc2b40e57528905df5a273f1026d4b01dcf8b' 
  AND token = '5Gyn29z3pfsEchJ78I7bgB0KuzTW5wEHyeRYs14LdQc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}