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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ae66b65e9f2c6580666f506b76325773b44808eeddcfba62d23125ff8c8a485' 
  AND token = 'nqXXtNecCIOYGWCHC2k8ZPeNokkbOZsxuMjv/vpLpH4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}