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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a88139eb017b0759804f5873673b7ee6eaaa5b59bc20988bd532729dc8d0e17' 
  AND token = '8rT+0km91JnqtYuX0pjeU834nhOxz7mz8B9NvUoVRyY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}