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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd363ef5c55ed3e298d21166804f0b0080a71a67d18fb9da9f3f1406bfbce08a6' 
  AND token = 'KxIUZc/tOeSLNzj8YBghVSF6kzNc0j5oQjIh19zOEhk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}