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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46755e50d2e17701740b9cf0c14096cabb17fbc8f106ae9a3c910ebb5b8fe438' 
  AND token = 'eq8ZQQYpGex4r1q9oJMaELtr+JU6cUlMbw/+6sotLgc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}