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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8221aa84a5642ad60742789f9464f2b786cc114010ace9f1689fc4d94eb8188' 
  AND token = 'AhEj5asJjC47IDSEKN9m+eeRuQ5fe0LhIYcyzhmWpFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}