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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e837264e018a739885f3ee705465443522629f7cd0d4b4e916ee390ea23bbf71' 
  AND token = '4swntqs424RROwUM11L3PC6sp3N2aabudTmRzJwIyNA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}