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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee21065296b2c65c40e0d69c8acef3684b4d998796665c8dcc6837c4aa5da7ae' 
  AND token = 'lr3HvH2wS9lpmXk8xL+UiE3OvpGerVFGyqhiRbAT3uc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}