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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e225f9b16267dd2b1dd296ffb34c84b1c5b1aede2b265f3c1592f98693b00b12' 
  AND token = '0/w3pks4Gk6JNf20NjqkHx3CGOlglF1tRpbBnnznmrc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}