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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9279c37723cfc57ed86e4f6b1e97947c1ce4f261eff0da556e9c275d090bc429' 
  AND token = 'ADfOIkdz5bqTTvsH2CmPifOtcSb5aZTftL5sRfXsqxY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}