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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5649ac55934ae7181278c5e15f10603acfcc31026bb3dbb0167943f2313c3df' 
  AND token = '7XuRWoFtqXiBs+PT7iR178y6MTDJ6MmdSVo3NgVr32E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00127

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}