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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c53b8fb0dd3d853b88864db856639651f33172cdb4872a074f25f28be1046ddf' 
  AND token = 'aC7rz6xxqr7hdft83SkskUmscxttEl36ujk12Cye3Wo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}