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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49cc00e9ec0a13559478f97f20edd4f4af160f938bb1082f3c594bcb42abb4c7' 
  AND token = 'Td2HA85uJiw2FnY8+Af6Oe3Azl/uVcChccB+cpr30r0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}