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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cc1e64fe5d82f0df99d7fb311fd440325f24b49f3efa62bbfc92473ff08e18f' 
  AND token = 'x3T/VGIjbeVMNqcocKiyLWX7Bs+LpgD2meub6hfdXuQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}