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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ab1e6694f737125720407c2a6e1a520f9d721c4a2050d5fc5d97b0c8a2d79d4' 
  AND token = 'P4JCKRWn0Q6fjTh125UsnUiEhrnzLFHPYxk4YuSTjsA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}