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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa80c357e7196ff287e0c9069b182a3a16e17c04559eb3465fa7e906d7c002cc' 
  AND token = '6MTbd3obdjwYMmz7v5mRdBIp0KyBokC2mokXvXeCJZg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}