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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc1a2b26782345723ba25ed4aa28829d23ad807ece4a718f12e9a854a149ab48' 
  AND token = 'R2Lt6AeTwzdj5D9enadXVmOZhHLGQudJP74u11UiFe0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}