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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f33cfb6c35edc64234c89f4ba5d177973e2200b4e3462fa19993d4fbfb6a75a' 
  AND token = 'VtY7ZM8c0eoKkI9jGJflMK4BZioKTDabIkhWHSxwhYQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}