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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f44c5255df2ea4eaa2518e3843657b6fe42278a8845b2a2c2dc0737458d7dcc2' 
  AND token = 'jusEQ64LzDcvy23F74ARgpsYb1NFlC0dAPv6y9AOGYE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}