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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18ae0e51add3a9a226b0f3f3ca9b2828196f5e1ed3daa2da0c0192ad32a13800' 
  AND token = 'kFPuxhf92d1BQRf4JsjqevK06pXTANmCTepc9lcMnTs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}