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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c43e62594d6e352a910688340838b5ad3e03dec128700e1ab93b14601091982f' 
  AND token = 't9YyO//dWbHaXWDEV4rgEJ7MVhsPydaZppqFJniEk+Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}