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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61c42e899e3aac4c69dfca7987edb40aa528c1225d32d1fe5f576803c5aa4871' 
  AND token = 'ub+1yZP0a52i66/MXsKRuMiwZ61CTQ7EbPhsNW1SSUQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}