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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b446c8b45a8a63e99dda901a5418c3c8c4d501a8485b1e0b97135a676cf3562e' 
  AND token = 'Zan/XBQJQ8//YvyUrA1WKDHtdQ8lFtfUAgiWqQAh6wU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}