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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41f0578a5d4d1aeeac5785d31d773106320e89a65b2cff9e1425a5c4a217175a' 
  AND token = 'bJckPdaZxhcqPyKKy83LPqeyf8vAxq9KW4qmbBwt/HI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}