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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '067e50439dc26d70434cba9a13d8de17b723dfc9f37e50b7ee26c1546f3e7582' 
  AND token = 'MakVnR7i9mYQ9VW0ErBs03NQf0bWE2/Q4HTIHMZQvJA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}