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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a8a29fd1e6330e619ff3aef4348d2ec61e711b7fc6e3bd84e55739b219a337b' 
  AND token = 'ZXKI+RkrMCV+KBKS4UowsCi9tVqW/i7Bd6f68fi/0Fo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}